Bilateral swelling of the salivary glands and sicca symptoms : an unusual differential diagnosis

  • A 68-year-old woman presented with bilateral swelling of the salivary glands, sicca symptoms of eyes and mouth, itching, fatigue and weight gain of about 5 kg in the last 2–3 years. As part of a careful diagnostic work up including lab tests for antinuclear antibodies (ANA), antibodies to extractable nuclear antigens (ENA), anti-neutrophilic cytoplasmatic antiobodies (ANCA), immunoglobulin (Ig)G4, a whole body computed tomography (CT) and a parotid biopsy several rheumatic diseases such as Sjoegren's syndrome, IgG4-related disease and sarcoidosis were ruled out and, considering a very high titre of IgE, Kimura's disease was diagnosed. The case and a short review of the literature are presented.

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Author:Jürgen BraunORCiDGND, Thomas MairingerGND, Oliver KaschkeGND, Kai Alexander BehrendtGND, Josef Ramsbacher, Kirsten KarbergGND
Parent Title (English):RMD Open
Subtitle (English):Kimura's disease, a rare allergic condition with a high IgE serum level : a case report and review of the literature
Publisher:BMJ Publishing Group
Place of publication:London
Document Type:Article
Date of Publication (online):2024/02/01
Date of first Publication:2023/05/10
Publishing Institution:Ruhr-Universität Bochum, Universitätsbibliothek
Tag:Open Access Fonds
Issue:2, Article e003135
First Page:e003135-1
Last Page:e003135-5
Article Processing Charge funded by the Deutsche Forschungsgemeinschaft (DFG) and the Open Access Publication Fund of Ruhr-Universität Bochum.
Institutes/Facilities:Rheumazentrum Ruhrgebiet
Dewey Decimal Classification:Technik, Medizin, angewandte Wissenschaften / Medizin, Gesundheit
open_access (DINI-Set):open_access
Licence (English):License LogoCreative Commons - CC BY-NC 4.0 - Attribution-NonCommercial 4.0 International