Detection of SARS-CoV-2 pneumonia

  • \(\bf Background:\) Developing therapeutic strategies for a SARS-CoV-2 infection is challenging, but first the correct diagnosis has to be made. Unspecific upper and lower respiratory tract symptoms can be misleading; hence, a nasopharyngeal swab test with a real-time reverse-transcription-polymerase chain reaction is of great importance. However, early viral clearing jeopardizes a sound diagnosis of COVID-19. \(\textbf {Case presentation:}\) We report on two Caucasian patients who had negative pharyngeal swab tests at the onset of SARS-CoV-2 pneumonia. In one patient, the virus was not even detectable in bronchoalveolar lavage despite typical radiomorphologic changes. \(\bf Conclusions:\) Negative PCR findings in both the pharynx and bronchoalveolar lavage do not exclude COVID-19 pneumonia. Computed tomography is a crucial diagnostic prerequisite in this context.

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Author:Felix Sebastian SeibertORCiDGND, Daniela TomaGND, Frederic BauerGND, Krystallenia PaniskakiGND, Moritz AnftGND, Benjamin Johannes RohnGND, Simon WangGND, Diana RacovitanGND, Nina BabelORCiDGND, Timm WesthoffORCiDGND
URN:urn:nbn:de:hbz:294-95526
DOI:https://doi.org/10.1186/s13256-020-02551-1
Parent Title (English):Journal of medical case reports
Subtitle (English):two case reports
Publisher:BioMed Central
Place of publication:London
Document Type:Article
Language:English
Date of Publication (online):2023/01/02
Date of first Publication:2020/12/11
Publishing Institution:Ruhr-Universität Bochum, Universitätsbibliothek
Tag:COVID-19; SARS-CoV-2; Swab test
Volume:14
Issue:Article 242
First Page:242-1
Last Page:242-4
Note:
Dieser Beitrag ist auf Grund des DEAL-Springer-Vertrages frei zugänglich.
Institutes/Facilities:Marienhospital Herne, Medizinische Klinik I
Dewey Decimal Classification:Technik, Medizin, angewandte Wissenschaften / Medizin, Gesundheit
open_access (DINI-Set):open_access
Licence (English):License LogoCreative Commons - CC BY 4.0 - Attribution 4.0 International

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