Incidence, recurrence and management of electrical storm in Brugada syndrome
- \(\bf Background:\) Brugada syndrome (BrS) is associated with ventricular tachyarrhythmias. However, the presence of electrical strom (ES) and its management still debated. \(\bf Objectives:\) We present the outcome and management of 44 BrS patients suffering from ES. \(\bf Methods:\) A systematic literature review and pooled analysis Through database review including PubMed, Web of Science, Cochrane Libary and Cinahl studies were analyzed. Evidence from 7 reports of 808 BrS patients was identified. \(\bf Results:\) The mean age of patients suffering from ES was 34 \(\pm\) 9.5 months (94.7% males, 65.8% spontaneous BrS type I). Using electrophysiological study ventricular tachycardia/ventricular fibrillation were inducible in 12/23 (52.2%). Recurrence of ES was documented in 6.1%. Death from ES was 8.2% after a follow-up of 83.5 \(\pm\) 53.4. In up to 27 ES resolved without treatment. External shock was required in 35.6%, internal ICD shock in 13.3%, Overdrive pacing, left cardiac sympathetic block and atropin in 2.2%. Short-term antiarrhythmic management was as the following: Isopreterenol or Isopreterenol in combination with quinidine 35.5%, orciprenaline in 2.2%, quinidine 2.2%, disopyramide 2.2% or denopamide 2.2%. However, lidocaine, magensium sulfate, mexiletine and propanolol failed to control ES. \(\bf Conclusion:\) Although ES is rare in BrS, this entity challenges physicians. Despite its high mortality rate, spontaneous termination is possible. Short-term management using Isoproterenol and/or quinidine might be safe. Prospective studies on management of ES are warranted.
Author: | Ibrahim El-BattrawyORCiDGND, Gretje RoterbergORCiDGND, Jacqueline KowitzORCiDGND, Assem AweimerORCiDGND, Siegfried LangGND, Andreas MüggeORCiDGND, Xiao-Bo ZhouGND, Ibrahim AkinORCiDGND |
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URN: | urn:nbn:de:hbz:294-103668 |
DOI: | https://doi.org/10.3389/fcvm.2022.981715 |
Parent Title (English): | Frontiers in cardiovascular medicine |
Publisher: | Frontiers Media |
Place of publication: | Lausanne, Schweiz |
Document Type: | Article |
Language: | English |
Date of Publication (online): | 2023/11/10 |
Date of first Publication: | 2022/10/25 |
Publishing Institution: | Ruhr-Universität Bochum, Universitätsbibliothek |
Tag: | Open Access Fonds Brugada; cardiac death; complications; electrical storm; outcome |
Volume: | 9 |
Issue: | Article 981715 |
First Page: | 981715-1 |
Last Page: | 981715-7 |
Note: | Article Processing Charge funded by the Deutsche Forschungsgemeinschaft (DFG) and the Open Access Publication Fund of Ruhr-Universität Bochum. |
Institutes/Facilities: | Berufsgenossenschaftliches Universitätsklinikum Bergmannsheil, Medizinische Klinik II, Kardiologie und Angiologie |
Dewey Decimal Classification: | Technik, Medizin, angewandte Wissenschaften / Medizin, Gesundheit |
open_access (DINI-Set): | open_access |
Licence (English): | Creative Commons - CC BY 4.0 - Attribution 4.0 International |