Facilitators and barriers of vaccine uptake in patients with autoimune inflammatory rheumatic disease

  • \(\bf Objectives\) Patients with autoimmune inflammatory rheumatic diseases (AIRD) often have lower vaccination coverage rates compared with the general population, despite being disproportionately affected by infectious complications. We aim to systematically review the literature regarding vaccination willingness and hesitancy in AIRD. \(\bf Methods\) A scoping review was conducted in PubMed, EMBASE and the Cochrane Library in June 2021. Study selection was performed by two independent reviewers and data were extracted using a standardised form. Risk of bias was assessed using instruments from McMaster University. Identified barriers were categorised into the WHO’s measuring behavioural and social drivers (BeSD) of vaccination conceptual model. \(\bf Results\) The search yielded 1644 hits of which 30 publications were included (cross-sectional studies based on interviews (n=27) and intervention studies (n=3)). The majority of studies reported barriers to influenza and pneumococcal vaccination only (n=9) or in combination with another vaccination (n=8) from the patients’ perspective. Only one study assessed the view of rheumatologists. Coverage of domains matched to the BeSD model suggests a lack of awareness of infection risk by both patients and physicians. Patients mainly mentioned behavioural and social factors that negatively influenced their willingness to be vaccinated while physicians mentioned organisational deficits as major barriers. \(\bf Conclusions\) The view on vaccination in patients with AIRD diverges between patients and rheumatologists. Our results show that in-depth counselling on vaccines is important for patients, whereas physicians need support in implementing specific immunisation recommendations. The themes identified provide a starting point for future interventions to improve vaccine rates in patients with AIRD.

Download full text files

Export metadata

Additional Services

Share in Twitter Search Google Scholar
Metadaten
Author:Silke NeusserORCiDGND, Anja NeumannGND, Pauline zur NiedenGND, Christian SpeckemeierORCiDGND, Sarah SchlierenkampGND, Anke WalendzikGND, Ute KarbachORCiDGND, Ioana AndreicaORCiDGND, Kristina VaupelGND, Xenofon BaraliakosORCiDGND, Uta KiltzORCiDGND
URN:urn:nbn:de:hbz:294-103570
DOI:https://doi.org/10.1136/rmdopen-2022-002562
Parent Title (English):RMD Open
Subtitle (English):a scoping review
Publisher:BMJ Publishing Group
Place of publication:London, Vereinigtes Königreich
Document Type:Article
Language:English
Date of Publication (online):2023/11/10
Date of first Publication:2022/12/12
Publishing Institution:Ruhr-Universität Bochum, Universitätsbibliothek
Tag:Open Access Fonds
Volume:8
Issue:2, Article e002562
First Page:e002562-1
Last Page:e002562-14
Note:
Article Processing Charge funded by the Deutsche Forschungsgemeinschaft (DFG) and the Open Access Publication Fund of Ruhr-Universität Bochum.
Institutes/Facilities:Rheumazentrum Ruhrgebiet
Dewey Decimal Classification:Technik, Medizin, angewandte Wissenschaften / Medizin, Gesundheit
open_access (DINI-Set):open_access
faculties:Medizinische Fakultät
Licence (English):License LogoCreative Commons - CC BY-NC 4.0 - Attribution-NonCommercial 4.0 International